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- People with active or recent cancer history (the trial record contains a small number of cancers in the 12-week oral arm
(7) M J Hsieh, H T Liu, C N Wang, H Y Huang, et al (2017)
Lau DCW, Erichsen L, Francisco AM, Satylganova A, le Roux CW, McGowan B, et al
The problem is that translation from rodent models to human outcomes is notoriously unreliable, and we've been burned by promising animal data that didn't pan out in humans more times than anyone wants to count
The most commonly reported side effects for both agents are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
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